People in quarantine hotels in England have been told they can leave confinement, as long as they have tested negative for Covid.
Health Secretary Sajid Javid also confirmed guests will be refunded for the days they have not used.
It comes after the government took all 11 countries off its travel red list earlier on Wednesday.
From late November, UK arrivals from these places had to book and pay for an approved hotel and isolate for 10 days.
But on Tuesday, Health Secretary Sajid Javid said the Omicron Covid variant had spread so widely that the rules were no longer effective.
According to a letter from the Department for Health, hotel guests will be allocated time slots to leave, organised by floor, from 16:00 GMT onwards on Wednesday.
People have been advised they are required to stay until formally told they can leave. Guests will be asked for details of their onward destinations for test and trace.