Yet surprisingly little is known about the diverse neurological effects of the fungus’s psychoactive compound, psilocybin, making it difficult to predict how the drug might ultimately benefit the community as a medicine.
A study led by Washington University School of Medicine psychiatrist Joshua Siegel tracked brain changes in seven healthy adults before, during, and after taking a high dose of psilocybin, identifying disruptions in connectivity that persisted for weeks in some areas of the brain.